Quality Standards of Safoof-e-muhazzil, an Anti-obesity Unani Formulation

Objective: The objective of this study is to establish the quality standards of Safoof-e-Muhazzil (SEMZ), a polyherbal Unani formulation for the treatment of overweight and obesity. Methods: The quality standards of SEMZ were established as per WHO guidelines including heavy metal residues, pesticides residue, aflatoxins, microbial load, GC-MS analysis and HPTLC fingerprinting analysis. Results: The results of standardization parameters showed total ash (10.73±1.23 %), acid-insoluble ash (1.47±0.21%), water-soluble ash (2.91±0.11%), alcohol-soluble extractive (24.95±1.47%), water-soluble extractive (37.46±2.14%), loss on drying (10.03±0.42 %), pH-value for 1% solution (6.01) and 10 % solution (5.3) at 25±2 oC, fat content (14.13±0.10 %), resin content (9.475±1.2 %) and heavy metals residue, pesticides residue, aflatoxins, microbial load complies with official limits. Conclusion: Data’s evolved in this investigation may be used in laying down Pharmacopoeial standards for the formulation studied, as standardization of herbal medicines as well as polyherbal formulations are absolutely essential and is the need of the hour.